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A group of scientists from South Korea has created a new method for labeling neurons in the brain to study conditions like Alzheimer's, Parkinson's, and stroke. This technology, called NeuM (Neuronal Membrane-selective), allows researchers to observe changes in nerve cells over 72 hours.
NeuM works by marking the outer membranes of neurons, which helps visualize their structures and track changes in real-time. This is important for understanding how nerve cells work both in healthy conditions and during diseases.
Unlike existing methods, NeuM has high accuracy and can track neurons for a long time. It binds well to neuronal membranes, allowing detailed imaging and long-term observation.
Dr. Kim Yun Kyung from KIST's Brain Science Institute explained that NeuM can help distinguish between aging and degenerating neurons, aiding in understanding brain disorders and developing treatments. The team plans to improve NeuM further for better analysis of neurons in the future.
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