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There are many types of cancer treatments. But which ones work best varies from patient to patient. Currently, doctors determine which treatment to try for a patient based on where in their DNA, or genetic code, the error that caused the cancer is located.
But a new approach that groups patients by the changes in protein structure and function caused by that error, rather than by the location of the changes in DNA, could lead to both more inclusive clinical trials and better treatment matches for patients.
I am part of a team that researches targeted therapies for cancer and ways to make treatment more patient-specific. A recent study by our research team determined that grouping DNA errors by structure may better personalize cancer therapies.
Targeted therapies hone in on cancer cells
Mutations are errors made during cell replication when the genetic material of that cell, or DNA, makes a new copy of itself. These mutations are usually harmless and caught by the cell’s proofreading machinery.
Read full article here: https://theconversation.com/a-new-way-to-organize-cancer-mutations-could-lead-to-better-treatment-matches-for-patients-168348
Image courtesy: https://www.gettyimages.com/detail/illustration/lungs-cancer-illness-or-lung-pneumonia-and-royalty-free-illustration/1223142317